A preterm neonate with diffuse rash at birth

Acute methotrexate poisoning with diffuse rash: a case report

Background: Methotrexate is an anti-metabolite drug and one of the folic acid analog that it can play an important and functional role in the treatment of many malignancies and inflammatory diseases. However, the development of petechiae (maculopapular rash) is a very rare complication. Case Presentation: The patient was a 77 years old woman, Aryan race, who was known a case of severe and prog...

A diffuse painful desquamating rash.

Diffuse, pruritic, papular rash.

Volume 88, Number 9 www.aafp.org/afp American Family Physician 605 A 34-year-old man presented with a pruritic, erythematous, papular rash that appeared two days earlier. The rash started on his trunk and back, then progressed to his arms and the proximal portion of his legs. He did not have pain, burning, or a tingling sensation. He did not have a fever or other systemic symptoms, and the revi...

Fever, diffuse rash and arthralgia.

A Newborn with a Blueberry Muffin Rash, Hepatosplenomegaly, Thrombocytopenia and Severe Cholestatic Jaundice at Birth

Neonatal cholestasis is characterized by an elevation of conjugated bilirubin. It occurs in approximately 1 in 2500 term infants. Gaucher Disease (GD) is an exceptionally rare cause of neonatal cholestasis. We report a male term newborn with a blueberry muffin rash, hepatomegaly and massive splenomegaly at birth. His total serum bilirubin (TSB)/direct was 13.5/11.9 mg/dL, and platelet count 20,...